Enterosgel accelerate the efficiency of standard treatment of allergic diseases
Enterosgel® improves the efficiency of treatment of allergic diseases, due to the following mechanisms:
- normalizes the function of the digestive tract and immune system;
- restores the normal composition of intestinal microflora;
- reduces antigenic load on the digestive system and immune barrier of the intestine;
- reduces the level of sensitization;
- binds food and non-food allergens in the digestive tract;
- reduces the severity and duration of exacerbation of skin and respiratory allergies, increases the duration of remission and reduces the number of relapses.
Enterosgel does not contain substances that can cause allergic or toxic reactions
The high effectiveness of adsorbent Enterosgel for reduction of endogenous intoxication and intestinal dysbiosis.
The data indicate that Enterosgel is a highly selective enterosorbent, it has a wide range and the highest sorption selectivity factor, its long-term use is possible – up to six months.
Enterosgel has the following properties:
- Large adsorption capacity, 2.5 times higher than in other types of sorbents;
- Cytoprotective properties;
- High biocompatibility with intestinal tissues;
- Does not damage GIT mucous membranes;
- Hydrophobic, does not penetrate through GIT mucous membranes;
- Forms hydrogel enveloping mucosa;
- Adheres pathogenic organisms;
- Selectively acts on the intestinal microbiocenosis.
Enterosgel is not absorbed, is not metabolized and excreted unchanged
Mechanism of Intoxication
Endotoxins are in large part responsible for the dramatic clinical manifestations of infections with pathogenic Gram-negative bacteria.
Epidemiological studies have previously shown that increased endotoxin load, which can be a result of increased populations of endotoxin producing bacteria in the intestinal tract, is associated with certain obesity-related patient groups (Moreno-Navarrete, JM et al., 2011).
Enterosgel adsorbs selectively lipopolysaccharides. Large lipopolysaccharide molecules coprecipitate in the gel and are excreted. A daily dose of Enterosgel binds 410 mg of lipopolysaccharide (LPS).
[Nikolaev, V.G (2010). Enterosgel (in eng). Kharkov. p. 39. ISBN 978-966-425-006-8. Helmut Brade (1999). Endotoxin in Health and Disease. New York: Taylor & Francis. p. 962. ISBN 0824719441.]